Jesus is about a high profile assassin who plans to fake his own death, laying low from all the mafia hitmen and the FBI that are after him. He plans to live the rest of his life with the money he could get from smuggling the drugs he stole from the mafia gangs - one of the reason he is chased. His plan fails and he couldn't get those drugs his old time friend hid for him, because they somehow happened to be concealed in a school's wall, with a super strength blackboard in front of it.
He has no choice but to pose as a high school teacher to guard his stash, trying his best not to get caught while being involved in crime cases.